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Bile acid

Order number Description Quantity Delivery time CE
TB 450-22 Bile Acid Control Set 6x5 ml 1-3 days x

Bile Acid Control Set

Bile Acids Controls are designed for use in the assay of bile acids per Trinity Biotech Procedure No. 450 to verify procedure reliability. Set contains 3x5 ml each of a normal control and an abnormal control.

Trinity Biotech Bile Acids reagents are intended for the quantitative, enzymatic determination of bile acids concentration of serum at 530 nm.
Bile acids are present in most body fluids with the highest concentrations being found in bile. The major bile acids are cholic acid, chenodeoxycholic acid, deoxycholic acid and lithocholic acid. Bile acids, after conjugation with glycine or taurine and sometimes with glucuronide or sulfate esters, are secreted into bile and undergo an enterohepatic circulation. Serum bile acids originate from the intestinal absorption of bile acids. An increase in serum bile acids concentration in the fasting state or post-prandial is considered to be a specific indicator of liver disease. A decreased level indicates bile acid malabsorption, possibly due to ileal dysfunction. Bile acids concentration can be measured by chromatographic, spectrophotometric, or fluorometric procedures. They can also be determined by radioimmunoassay or similar competitive binding techniques, as well as by bioluminescence detection methods. Trinity Biotech Bile Acids reagents measure serum bile acids concentration enzymatically. The methodology is based essentially on the procedure of Mashige et al.



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