| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| TC 5450401 | TECHNOZYM® ADAMTS-13 INH ELISA; 96 tests | 1 kit | 7 days | x |
TECHNOZYM® ADAMTS-13 INH ELISA; 96 testsThe TECHNOZYM® ADAMTS-13 INH ELISA is a test for detection of human autoantibodies (IgG) in serum or plasma against ADAMTS-13, the protease which is responsible for cleaving unusually large vWF (ULvWF). The TECHNOZYM® ADAMTS-13 INH ELISA is a test for detection of human autoantibodies (IgG) in serum or plasma against ADAMTS-13, the protease which is responsible for cleaving unusually large vWF (ULvWF). Most of these autoantibodies inhibit ADAMTS-13 activity and thus non-cleaved ULvWF accumulates in plasma. This is believed to be the major cause for thrombotic thrombocytopenic purpura (TTP). TECHNOZYM® ADAMTS-13 INH test makes it possible to differentiate between congenital (gene polymorphisms) and acquired (autoantibodies) TTP when coupled to an activity assay and to control efficacy of plasma exchange therapy.
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