| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| PB FDP12-10 | FXII Imm Depleted Plasma | 25x1 ml | 7-10 days | x |
FXII Imm Depleted PlasmaCRYOcheck Factor XII Deficient Plasma is recommended for use as a deficient substrate in clot-based factor XII assays using the activated partial thromboplastin time (APTT). Deficiencies in coagulation factors may have congenital or acquired etiologies and can compromise in vivo hemostasis. Factor XII (Hageman factor) is a single-chained glycoprotein with a molecular weight of 80,000 Da and is necessary for intrinsic coagulation. Plasma samples deficient in coagulation factor XII exhibit a prolonged APTT. Factor XII deficiency is commonly diagnosed through the use of a modified APTT assay. When a patient sample is mixed with factor XII deficient plasma, the degree of correction of the APTT is proportional to the level of factor XII in the patient plasma. |
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