| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| PB FDP8-10 | FVIII Imm. Depleted Plasma | 25x1 ml | 7-10 days | x |
FVIII Imm. Depleted PlasmaCRYOcheck Factor VIII Deficient Plasma is recommended for use as a deficient substrate in clot-based factor VIII assays using the activated partial thromboplastin time (APTT). Deficiencies in coagulation factors may have congenital or acquired etiologies and can compromise in vivo hemostasis. Factor VIII (antihemophilic A factor) is a glycoprotein with a molecular weight of at least 250,000 Da. It is present in vivo as a complex with vonWillebrand factor and is necessary for intrinsic coagulation. Plasma samples deficient in coagulation factor VIII exhibit a prolonged APTT. Factor VIII deficiency (hemophilia A) is commonly diagnosed through the use of a modified APTT assay. When a patient sample is mixed with factor VIII deficient plasma, the degree of correction of the APTT is proportional to the level of factor VIII in the patient plasma. |
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