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Reference & control plasmas

Order number Description Quantity Delivery time CE
TC 5450761 TECHNOZYM® ADAMTS-13 Activity Calibrator Set 5x0.5 ml 7-10 days x

TECHNOZYM® ADAMTS-13 Activity Calibrator Set

The TECHNOZYM® ADAMTS-13 Activity ELISA is a chromogenic test for the determination of
ADAMTS-13 activity in human plasma. ADAMTS-13 (a disintegrin-like and metalloproteinase
with thrombospondin type 1 motif 13) is an enzyme (vWF-cleaving protease or vWF-CP) that
specifically cleaves unusually large von Willebrand factor (vWF) multimers, which induce
platelet thrombus formation under high shear stress. If the activity of ADAMTS13 is lowered for
some reason, however, unusually large vWF multimers may accumulate within blood causing
thrombosis due to platelet aggregation, which in turn may lead to TTP (thrombotic
thrombocytopenic purpura).



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