| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| TB T5102 | TriniCAL Reference Plasma | 10 x 1 ml | 1-3 days | x |
TriniCAL Reference PlasmaTriniCAL Reference Plasma is an assayed human plasma that has been lyophilized to maintain the integrity of the constituents. It is intended for use as a reference plasma for the quantitation of coagulation proteins as well as a control in routine coagulation assays. Many procedures performed in the coagulation laboratory require the use of a wellcharacterized reference plasma to evaluate levels of clotting factor assays, inhibitors, and fibrinolytic proteins in blood specimens as well as to monitor assay variability and reagent decomposition. It is common practice to use freshly drawn pools of normal platelet-poor plasma from a relatively large number of healthy donors as this reference plasma. Factor assays, used to quantitate the percent activity of specific clotting factors in plasma, require dilutions of normal pooled plasma to prepare a standard curve. Routine coagulation assays, Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), and Thrombin Time (TT), use well-characterized normal plasmas as controls to check assay procedures and validate reagents. It is difficult to obtain and maintain a consistent and reliable normal pool. Using a large number of qualified donors (healthy, non-smoking, under no medication, etc.) does not ensure a standard with 100% activity for each hemostasis protein. Therefore, a standardized reliable reference plasma containing quantitated levels of the major hemostasis proteins is the optimal replacement for a normal pool. TriniCAL Reference Plasma is this type of reference plasma and may be used to prepare standard curves for factor assays and chromogenic assays as well as be used as a normal control for the PT, APTT, and TT assays. The assigned activity of each hemostasis protein included in TriniCAL Reference Plasma was calculated based on the results of multiple assays. All factors were assayed against WHO and other reference preparations in order to assure the reliability and accuracy of assigned values. |
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