| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| BM 252561 | MDA Thromboquik | 10x2.5 ml (10x30 tests) | 1-3 days | x |
MDA ThromboquikMDA® Thromboquik™ is a thrombin reagent (bovine) for use in the determination of the Thrombin Time (TT) in human plasma. The Thrombin Time assay is based on the ability of thrombin to catalyze the polymerization of fibrinogen into a fibrin clot. The mechanism involves the cleavage of peptides (fibrinopeptides A and B) from the amino-terminal ends of the alpha and beta chains of fibrinogen by the proteolytic action of thrombin. The resulting fibrin monomer molecules ultimately polymerize into a fibrin clot. The Thrombin Time assay is a qualitative screening assay used to detect abnormalities in this phase of coagulation. The assay is performed by adding a known quantity of low concentration thrombin reagent to a plasma specimen in vitro and measuring the Abnormalities affecting this stage of coagulation include quantitative and qualitative alterations in fibrinogen, increased fibrinolytic activity causing variations in Fibrin(ogen) Degradation Products (FDP), and interferences with fibrinogen polymerization. The Thrombin Time assay is also sensitive to heparin and other circulating antithrombins. |
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