| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| PF 121-03 | RVV-V | 1000 U | 10-15 days |
RVV-VRVV-V is a specific factor V activator from Russell’s viper venom. RVV-V is a serine proteinase, which converts the single-chain coagulation factor V into a light chain (80’000 g/mol) and a heavy chain (230’000 g/mol) with higher coagulant activity (factor Va). Apart from factor V, no other protein substrate for RVV-V is known. The amino acid sequence is 68% identical to that of batroxobin and 33% to that of the â-chain of human thrombin. Activated factor V is not stable and loses its activity within 20 hours at 37° C. Therefore, RVV-V is used to destabilize and selectively inactivate factor V in plasma and thus to prepare a routine reagent for the factor V determination. |
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