| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| GP FVLK | Factor V Leiden Test Kit | 100 tests | 10 days | x |
Factor V Leiden Test KitGradiLeiden V is a simple functional clotting test system itended for screening of resistance to Activated Protein C (APC) in plasma from individuals with the Factor V (Leiden) defect. It can also be performed on plasma from patients on stabilized oral anticoagulant or heparin therapy. For in vitro diagnostic use. Activated Protein C Resistance (APCr) is associated with a point mutation in the Factor V gene [Factor V (Leiden)]. The mutation results in the replacement of Arg506 (R) with Gln (Q) in the Factor V protein. This mutation slows the inactivation of factor Va by APC causing a hypercoagulable state. The presence of Factor V (Leiden) is the most common cause of inherited thrombophilia, accounting for 20% to 50% of cases. |
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