| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| PF 505-01 | Pefakit PiCT | 120 tests | 10-15 days | x |
Pefakit PiCTPefakit PiCT (Prothrombinase induced Clotting Time) is a plasma based functional assay for the determination of anticoagulant activity based on FXa and/or FIIa inhibition. Heparin and heparinoids like UFH, LMWH, pentasaccharide and danaparoid are anticoagulant drugs, which enhance the inhibitory action of the natural inhibitors antithrombin (AT) and partly also heparin cofactor II on FXa and/or FIIa. In many studies the efficacy of these drugs for the prevention and treatment of thromboembolic events has been shown. However these substances can also induce bleeding complications. In patients with renal insufficiency accumulation of the anticoagulant can occur following repeated application. Before spinal anesthesia in anticoagulated patients a control of the anticoagulant levels is recommended. The aPTT does not reliably detect LMWH, danaparoid and pentasaccharide. Thus in many clinics no monitoring of LMWH, danaparoid or pentasaccharide is available. |
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