| Order number | Description | Quantity | Delivery time | CE |
|---|---|---|---|---|
| PF 800191 | Pefakit Reptilase Time, 30 tests | 1 set | 10-15 days | x |
Pefakit Reptilase Time, 30 testsPefakit Reptilase Time is a plasma based functional assay intended to be used for the determination of the Reptilase induced clotting time (= Reptilase Time, ReT) by a manual method or on a semi- or fully automated system. The ReT has been recommended for the investigation of the last phase of blood coagulation. Pefakit Reptilase Time reagent contains a standardized amount of Batroxobin, the thrombin-like proteolytic enzyme from Bothrops atrox venom. In contrast to thrombin which releases the fibrinopeptides A and B from fibrinogen, Batroxobin specifically splits off only fibrinopeptide A. Batroxobin does not inactivate or activate other hemostasis proteins or platelets. In contrast to thrombin Batroxobin is not inhibited by heparin, heparinoids, antithrombin, hirudin, aprotinin or antifibrinolytic drugs. Fibrinogen degradation products (FDP), however, prolong the ReT by interfering with fibrin polymerization. The ReT can therefore be used for the detection of FDP and differentiating between fibrin synthesis disturbances and influence of heparin in combination with Thrombin Time (TT). |
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