Diabetes
| Order number |
Description |
Quantity |
Delivery time |
CE |
| TBD 03-01-0048 |
Ultra2-A1c (A1c Testing Only) |
1x |
|
x |
Ultra2-A1c (A1c Testing Only)
Glycated haemoglobin (HbA1c) has a particular clinical interest in diabetes mellitus. Measurement of glycated haemoglobin is a clinically useful means of assessing glycemic control in diabetics. Glycated haemoglobin values reflect blood glucose levels over the circulatory half-life of the erythrocyte and correlate significantly with mean blood glucose levels during that time.Therefore, measurement of glycated haemoglobin provides a means, independent of multiple measurements such as patient records of self-monitored blood glucose, for assessing the overall efficacy of therapy.It is recommended an HbA1c test 3 times per year minimum for monitoring the glycemic in diabetics.There is significant evidence that maintaining good glycemic control has a positive impact on reducing the development of the long-term complications of diabetes.
The Ultra2-A1c combines the advantages of boronate affinity separation with the precision, convenience and automation of high-performance liquid chromatography.
Boronate affinity chromatography is free from common interferences such as haemoglobin variants, non-glycation modifications and storage-related hemichromes. Boronate affinity chromatography requires no sample pretreatment to remove the labile component, since only stable (ketoamine-linked) GHb is retained by the boronate.
Compared to ion-exchange techniques, affinity separation is also less sensitive to quantitative errors caused by minor fluctuations in reagent pH and ionic strength.
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